When Will Malaria Meds Stop Working In Africa?
“The continent should take the matter of resistance very, very seriously...Resistance should be seen as an emergency situation.”
- Artemisinin resistance was first confirmed in Rwanda (2021) and Uganda (2022), with subsequent reports in Ethiopia and the Democratic Republic of Congo by 2025.
- Treatment failure rates for dihydroartemisinin-piperaquine in parts of Uganda reached 15% in 2025, the WHO threshold for changing first-line therapy.
- The Pfkelch13 gene mutation, which slows parasite clearance, has now been detected in at least 12 African countries.